SAP30 Antilichaam - middengebied HRP (ARP38393_T100-HRP)

Sin3A-associated protein, 30kDa

8819

O75446

NP_003855

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human SAP30

Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. SAP30 is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones.Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A pseudogene of this gene is located on chromosome 3.

HDAC3; CUL4B; DDB1; HDAC1; SIN3A; UBC; HDAC2; BRMS1L; ING1; ARID4A; SAMSN1; ZNF395; UBASH3B; RBBP7; RBBP4; CHD4; ALL1; TAF6; SMARCA2; SAP25; RBP1; HIST2H2BE; PCBD1; ID3; SAP30BP; HIST2H4A; HBP1; HIST1H2AL; BRMS1; CIR1; HIST3H3; NCOR1; NCOR2; MXD1; YY1; HT

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

0.5 mg/ml

Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

23kDa

Sironi, E., (2004) J. Cutan. Pathol. 31 (4), 318-322

Wet Ice

220

SAP30

SAP30

Rabbit

Histone deacetylase complex subunit SAP30

NM_003864

YQLQVNTLRRYKRHFKLPTRPGLNKAQLVEIVGCHFRSIPVNEKDTLTYF

SAP30