
SAR-442257
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
SAR442257 is a humanized IgG4-S228P, kappa monoclonal antibody targeting CD38 and CD28 on multiple myeloma cells and co-stimulates CD3 and CD28 on T cells[1].
12352203
CD28; CD3; CD38
Immunology/Inflammation
Cancer-programmed cell death
Cancer
99.0
[*]S[R442257]
(145.44 kDa)
[1]Grab AL, et al. Pre-Clinical Assessment of SAR442257, a CD38/CD3xCD28 Trispecific T Cell Engager in Treatment of Relapsed/Refractory Multiple Myeloma. Cells. 2024 May 20;13 (10) :879.
Dry Ice
-80°C
http://file.medchemexpress.com/batch_PDF/HY-P991183/SAR-442257-SDS-MedChemExpress.pdf
Inhibitory Antibodies
Phase 1
Beschrijving
SAR442257 is a humanized IgG4-S228P, kappa monoclonal antibody targeting CD38 and CD28 on multiple myeloma cells and co-stimulates CD3 and CD28 on T cells[1].
Specificaties
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