Gecertificeerd

SAR-446523

Name: SAR-446523
Brand: Genprice.nl
SKU: 26526989
Availability: InStock

Catalog #: HY-P991587

Maat: 1 Each

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%

BTW niet inbegrepen

Gratis verzending vanaf €100

Aantal:

Technische Specificaties

Description

SAR-446523 is a humanized IgG1 monoclonal antibody inhibitor targeting GPRC5D. SAR-446523 significantly induces antibody-dependent cell-mediated cytotoxicity (ADCC) . SAR-446523 has potent antitumor activity with improvement of mouse survival in NK humanized NOG huIL15 transgenic mice model bearing MM cells. SAR-446523 can be used for multiple myeloma (MM) research[1].

UNSPSC

12352203

Target

Orphan GPCR

Related Pathways

GPCR/G Protein

Applications

Cancer-programmed cell death

Field of Research

Cancer

References & Citations

[1]Bonnevaux H, et al. Pre-clinical development of a novel anti-GPRC5D inducing potent anti-tumor effect through enhanced antibody-dependent cell-mediated cytotoxicity (ADCC) for multiple myeloma[J]. Cancer Research, 2024, 84 (6_Supplement) : 2727-2727.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P991587/

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Beschrijving

SAR-446523 is a humanized IgG1 monoclonal antibody inhibitor targeting GPRC5D. SAR-446523 significantly induces antibody-dependent cell-mediated cytotoxicity (A

Specificaties

ProductnaamSAR-446523

Categorie

Beschikbare grootte1 Each

CatalogusnummerHY-P991587

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