SARS-CoV-2 (COVID-19) NSP15 Peptide

Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1) . The disease is the cause of the 2019–20 coronavirus outbreak (2) . The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. NSP15 is a Mn2+-dependent, uridylate-specific enzyme, which leaves 2'-3'-cyclic phosphates 5' to the cleaved bond.

43740578

P0DTC1

6VWW_B

Peptides

200 ug/mL

PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide

Blue Ice

Store SARS-CoV-2 (COVID-19) NSP15 Peptide at -20˚ C, stable for one year.

SARS-CoV-2 (COVID-19) NSP15 Peptideis used for blocking the activity of theSARS-CoV-2 (COVID-19) NSP15 Antibody

ORF1a polyprotein; ORF1ab polyprotein

Severe acute respiratory syndrome coronavirus 2

Gorbalenya. bioRxiv: 2020.

Hui et al. Int J Infect Dis. 2020;91:264-266.

Uridylate-specific endoribonuclease, NendoU, NSP15, Non-structure protein 15

Blocking

SARS-CoV-3

1851775710

Liquid