SARS-CoV-2 (COVID-19) NSP8 Antilichaam

Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1) . The disease is the cause of the 2019–20 coronavirus outbreak (2) . The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. NSP8 plays a role in viral RNA synthesis (3,4,5) . Forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, it may synthesize substantially longer products than oligonucleotide primers (6) .

43740578

P0DTC1

YP_009742615.1

Virus

9159

Unconjugated

Primary Antibodies

Infectious Disease, COVID-19

SARS-CoV-2 (COVID-19) NSP8 Antibody is affinity chromatography purified via peptide column.

1 mg/mL

Predicted reactivity based on immunogen sequence: SARS-CoV NSP8 protein: (100%)

SARS-CoV-2 (COVID-19) NSP8 Antibody is supplied in PBS containing 0.02% sodium azide.

Blue Ice

SARS-CoV-2 (COVID-19) NSP8 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

Non-structural protein 8

ORF1a polyprotein; ORF1ab polyprotein

Severe acute respiratory syndrome coronavirus 2

Gorbalenya. bioRxiv: 2020.

Hui et al. Int J Infect Dis. 2020;91:264-266.

Gao et. al Science 2020;0:0-0

Yin et. al Science 2020;0:0-0

NSP8

ELISA, IHC

1826688925

Liquid