SARS-CoV-2 (COVID-19) Spike 26P Antilichaam [1C3H9]

In January of 2021 a new lineage of SARS-CoV-2, known as P.1 and named Gamma variant, was discovered in Japan and later spread in Brazil. It is considered a VOC (variant of concern) . This variant carries 10 mutations in spike protein, including N501Y, E484K and K417T in RBD, which can increase the affinity to the human ACE2 receptor. Enhanced transmission of the Gamma variant (P.1 lineage) was observed globally, which is 3.5 times more contagious as the original one. The Gamma variant affects the effectiveness of COVID19 vaccine and is resistant to neutralization to some extent due to the immune escape E484K mutation.

43740568

P0DTC2

QHD43416

Virus

PM-9583

1C3H9

Unconjugated

Primary Antibodies

Infectious Disease, COVID-19

Anti-SARS-CoV-2 Spike 26P antibody is Protein A purified.

1 mg/mL

Predicted reactivity based on immunogen sequence: SARS-CoV Spike proteins: (36.4%)

SARS-CoV-2 Spike 26P antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

SARS-CoV-2 Spike 26P antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG2b

It detects Spike S1 proteins of SARS-CoV-2 WT and variants except gamma variant.

S

Surface glycoprotein

Severe acute respiratory syndrome coronavirus 2

Voloch et al. Journal of Virology 2021, 95 (10) : e00119-21.

Wang et al. Cell Host & Microbe 2021, 29 (5) : 747-751.

Wang et al. Nature 592, 616-622.

SARS-CoV-2 Spike 156-157EF antibody: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Surface Glycoprotein, Spike protein

ELISA, WB

1791269090

Liquid