SARS-CoV-2 Nucleocapsid Control Antilichaam [4A1W0]

Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.

43740575

P0DTC9

#YP_009724397.2

Virus

HEK293 derived SARS-COV-2 Nucleocapsid, amino acids Ser2-Ala419

4A1W0

Unconjugated

Primary Antibodies

Infectious Disease, COVID-19

Affinity Purified, Endotoxin Level: < 1.0 EU/ug of the protein by LAL method.

1mg/ml

Supplied as a 0.2um filtered solution in PBS, pH 7.4.

None

Blue Ice

This antibody can be stored at 2&#730; C to -8&#730; C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20&#730; C to -80&#730; C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Human IgG

SARS-CoV-2

N

Nucleocapsid phosphoprotein

Severe acute respiratory syndrome coronavirus 2

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ELISA

1798174255

Liquid