![SARS-CoV-2 Spike RBD Nanobody, HRP-geconjugeerd Recombinant antilichaam [A1] (OACA12526)](/_ipx/q_80/productPlaceholder.webp)
SARS-CoV-2 Spike RBD Nanobody, HRP-geconjugeerd Recombinant antilichaam [A1] (OACA12526)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Surface glycoprotein
E2; GU280_gp02; Peplomer protein; spike glycoprotein; surface glycoprotein.
43740568
SARS-CoV-2 / COVID-19 Virus
Recombinant Human Novel Coronavirus Spike glycoprotein (S) (319-541aa) (CSB-YP3324GMY1 and CSB-MP3324GMY1b1)
• Recombinant Monoclonal Nanobody
HRP
Recombinant Monoclonal Antibody
Enzyme-linked immunosorbent assay
Affinity Purified
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. Binding to human ACE2 receptor and internalization of the virus into the endosomes of the host cell induces conformational changes in the Spike glycoprotein (PubMed:32142651, PubMed:32221306, PubMed:32075877, PubMed:32155444) . Binding to host NRP1 and NRP2 via C-terminal polybasic sequence enhances virion entry into host cell (PubMed:33082294, PubMed:33082293) . This interaction may explain virus tropism of human olfactory epithelium cells, which express high level of NRP1 and NRP2 but low level of ACE2 (PubMed:33082293) . The stalk domain of S contains three hinges, giving the head unexpected orientational freedom (PubMed:32817270) . Uses human TMPRSS2 for priming in human lung cells which is an essential step for viral entry (PubMed:32142651) . Can be alternatively processed by host furin (PubMed:32362314) . Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membrane fusion within endosomes.
Liquid
-20°C or -80°C
S
Spike glycoprotein
S
Beschrijving
SARS-CoV-2 Spike RBD Nanobody, HRP-geconjugeerd Recombinant antilichaam [A1] (OACA12526) Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
Recombinant Common timothy PHLPIV/Phl p 4 Protein, N-His
YZZ03001
100 μg
NP (4-hydroxy-3-nitrophenylacetate)
NP-BSA-03Low – 10 mg
10 mg
NP (4-hydroxy-3-nitrophenylacetate)
NP-BSA-03High – 10 mg
10 mg
ExactaCruz® Pipette Tip Reload System, 50-1250 μl, case
sc-201714
80 Racks/Case
Disc Membrane Hydrophobic PTFE, 0.22μm
CPTB14222
50 PCS
Rat Serum Albumin
CSB-NP000101r-01
1 mg
Denhardt's Solution (50X)
EC-915
50 mL
FKBP4, ID (FK506-binding Protein 4, Peptidyl-prolyl cis-trans Isomerase FKBP4, PPIase FKBP4, Rotamase, HSP-binding Immunophilin, HBI, FKBP52 Protein, 52kD FK506-binding Protein, 52kD FKBP, FKBP-52, 59kD Immunophilin, FKBP59, p59 Protein, FKBP-4, FKBP52)
MBS623609-01
0.2 mL
Recent gezochte producten
Recombinant Common timothy PHLPIV/Phl p 4 Protein, N-His
YZZ03001
100 μg
E030010N08Rik (m) -PR
sc-143217-PR
10 µM - 20 µL
C030019I05Rik siRNA (m)
sc-141806
10 µM
E030019B06Rik (m) -PR
sc-143221-PR
10 µM - 20 µL
C030019I05Rik (m) -PR
sc-141806-PR
10 µM - 20 µL
D030016E14Rik (m) -PR
sc-142768-PR
10 µM - 20 µL
Compound N003-0017
T131382-01
1 mg
Compound N003-0017
MBS5796320
Inquire