SARS-CoV-2 Spike S1 D614G Stabiele Trimer Recombinant zijn eiwit

Full-length soluble SARS-CoV-2 Spike protein (aa 16-1213) including a foldon trimerization motif, mutated Furin recognition site (R682S, R685S) and two stabilizing mutations (K986P and V987P) is fused at the C-terminus to a His-tag. Source: Expressed in HEK-293 cells. Reconstitution: Reconstitute with 250μl endotoxin-free water. Concentration: 0.2mg/ml after reconstitution. Background: The spike S1 protein of SARS-CoV-2 attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2) . A defined receptor-binding domain (RBD) on S1 mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

P0DTC2

ELISA

>90% by SDS-PAGE.

SARS-CoV-2 Spike S1 D614G Stable Trimer Recombinant His Protein lyophilized with PBS and 0.5% trehalose.

Shipped on Blue Ice

Shipped on ice packs. Upon arrival, Store at -20°C. Do not freeze-thaw multiple times. For maximum product recovery after thawing, centrifuge the vial before opening the cap.

The target protein is expressed with sequence (aa 16-1213) including a foldon trimerization motif, mutated Furin recognition site (R682S, R685S) and two stabilizing mutations (K986P and V987P) is fused at the C-terminus to a His-tag.