SARS-COV-2 Spike S1 Protein Antilichaam [7D10U4]

The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. The spike is essential for both host specificity and viral infectivity. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. It''s been reported that SARS-CoV-2 (COVID-19 coronavirus, 2019-nCoV) can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. The main functions for the Spike protein are summarized as: Mediate receptor binding and membrane fusion; Defines the range of the hosts and specificity of the virus; Main component to bind with the neutralizing antibody; Key target for vaccine design; Can be transmitted between different hosts through gene recombination or mutation of the receptor binding domain (RBD), leading to a higher mortality rate.

43740568

P0DTC2

YP_009724390.1

Virus

HEK293 derived SARS-COV-2 SPIKE S1, amino acids Val16-Arg685

7D10U4

Unconjugated

Primary Antibodies, Antibody Pairs

Infectious Disease, COVID-19

Affinity Purified, Endotoxin Level: < 1.0 EU/ug of the protein by LAL method.

1mg/ml

Supplied as a 0.2um filtered solution in PBS, pH 7.4.

None

Blue Ice

This antibody can be stored at 2&#730; C to -8&#730; C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20&#730; C to -80&#730; C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Rabbit IgG

SARS-CoV-2

ELISA Capture: Recommended Concentration: 1-4ug/mL, Sample: SARS-COV-2 Spike S1 Protein Antibody (CAP) ELISA Detection: Recommended Concentration: 0.05-0.2ug/mL, Sample: SARS-COV-2 Spike S1 Protein Antibody (DET) Standard: Recommended Concentration: 156-10000pg/mL, Sample: Recombinant SARS-COV-2 Spike S1 Protein with His tag

S

Surface glycoprotein

Severe acute respiratory syndrome coronavirus 2

Spike glycoprotein

ELISA

1796318598

Liquid