SARS-CoV Spike Antilichaam

SARS Spike Antibody: A novel coronavirus has recently been identified as the causative agent of SARS (Severe Acute Respiratory Syndrome) . Coronaviruses are a major cause of upper respiratory diseases in humans. The genomes of these viruses are positive-stranded RNA approximately 27-31kb in length. SARS infection can be mediated by the binding of the viral spike protein, a glycosylated 139 kDa protein and the major surface antigen of the virus, to the angiotensin-converting enzyme 2 (ACE2) on target cells. This binding can be blocked by a soluble form of ACE2.

1489668

P59594

P59594

Virus

3223

Unconjugated

Primary Antibodies

Infectious Disease, COVID-19

SARS-CoV Spike Antibody is affinity chromatography purified via peptide column.

1 mg/mL

Predicted reactivity based on immunogen sequence: SARS-CoV2 Spike protein: (identity 65%, homology 88%)

SARS-CoV Spike Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

SARS-CoV Spike antibody can be stored at 4˚ C up to one year. Antibodies should not be exposed to prolonged high temperatures.

IgG

SARS-CoV Spike antibody can be used for the detection of SARS-CoV Spike protein in ELISA. It will detect 2 ng of free peptide at 1 μ g/mL.

SARS-CoV Spike has one isoform (1255aa) .

S

Spike glycoprotein

SARS coronavirus

Marra et al. Science 2003;300:1399-404.

Rota et al. Science 2003;300:1394-9.

Navas-Nartin et al. J Neurovirol. 2004;10:75-85.

Li et al. Nature 2003;426:450-4.

32985653

SARS-CoV Spike antibody: E2, Spike glycoprotein, E2, S glycoprotein

ELISA

30173397

Liquid