SARS-CoV Spike Antilichaam

SARS-CoV Spike antibody: A novel coronavirus has recently been identified as the causative agent of SARS (Severe Acute Respiratory Syndrome) . Coronaviruses are a major cause of upper respiratory diseases in humans. The genomes of these viruses are positive-stranded RNA approximately 27-31kb in length. SARS infection can be mediated by the binding of the viral spike protein, a glycosylated 139 kDa protein and the major surface antigen of the virus, to the angiotensin-converting enzyme 2 (ACE2) on target cells. This binding can be blocked by a soluble form of ACE2.

1489668

P59594

P59594

Virus

3225

Unconjugated

Primary Antibodies

Infectious Disease, COVID-19

SARS-CoV Spike antibody is affinity chromatography purified via peptide column.

1 mg/mL

Predicted reactivity based on immunogen sequence: SARS-CoV2 Spike protein: (identity 40%, homology 56%)

SARS-CoV Spike antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

SARS-CoV Spike antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

SARS-CoV Spike antibody can be used for the detection of SARS-CoV Spike protein in ELISA. It will detect 5 ng of free peptide at 1 μ g/mL.

SARS-CoV Spike has one isoform (1255aa) .

S

Spike glycoprotein

SARS coronavirus

Marra et al. Science 2003;300:1399-404.

Rota et al. Science 2003;300:1394-9.

Navas-Nartin et al. J Neurovirol. 2004;10:75-85.

Li et al. Nature 2003;426:450-4.

SARS-CoV Spike antibody: E2, Spike glycoprotein, E2, S glycoprotein

ELISA

30173397

Liquid