SART3 Antilichaam - middengebied: FITC (ARP34329_P050-FITC)

Squamous cell carcinoma antigen recognized by T cells 3

P100, p110, DSAP1, TIP110, p110 (nrb), RP11-13G14

9733

Q15020

NP_055521

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human SART3

SART3 is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. SART3 is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This protein is thought to be involved in the regulation of mRNA splicing. The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

APBB1; PRPF3; Usp15; AMOT; SF3B1; NUP160; LRPPRC; THRAP3; BCLAF1; VARS; UBC; SUMO2; RAB1A; NEFM; IARS; HIF1A; DSG2; DHX9; MEPCE; HIST2H2BE; HIST2H2AC; RNF2; BMI1; RUFY1; NRBP1; PSME4; AKAP2; COPS5; NUP50; POP7; ARHGEF10; PSMB3; PSMA5; PSMA3; POLR2H; CAST

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 91%; Zebrafish: 77%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

110kDa

Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007)

Wet Ice

963

SART3

SART3

Rabbit

Squamous cell carcinoma antigen recognized by T-cells 3

NM_014706

VKDLRLVTNRAGKPKGLAYVEYENESQASQAVMKMDGMTIKENIIKVAIS