SART3 Antilichaam - N-terminalgebied: FITC (ARP39128_T100-FITC)

Squamous cell carcinoma antigen recognized by T cells 3

P100, p110, DSAP1, TIP110, p110 (nrb), RP11-13G14

9733

Q15020-2

AAK69347

Human, Rat, Dog, Guinea Pig, Horse, Pig

The immunogen is a synthetic peptide directed towards the N terminal region of human SART3

SART3 is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. SART3 is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This protein is thought to be involved in the regulation of mRNA splicing.

APBB1; PRPF3; Usp15; AMOT; SF3B1; NUP160; LRPPRC; THRAP3; BCLAF1; VARS; UBC; SUMO2; RAB1A; NEFM; IARS; HIF1A; DSG2; DHX9; MEPCE; HIST2H2BE; HIST2H2AC; RNF2; BMI1; RUFY1; NRBP1; PSME4; AKAP2; COPS5; NUP50; POP7; ARHGEF10; PSMB3; PSMA5; PSMA3; POLR2H; CAST

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

IHC, WB

SART3 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

0.5 mg/ml

Dog: 77%; Guinea Pig: 79%; Horse: 79%; Human: 100%; Pig: 86%; Rat: 79%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

40kDa

Liu, Y., (2002) J. Biol. Chem. 277 (26), 23854-23863

Wet Ice

364

SART3

SART3

Rabbit

Squamous cell carcinoma antigen recognized by T-cells 3

NM_014706

TSASEPEAESKAGPKADGEEDEVKAARTRRKVLSRAVAAATYKTMGPAWD