SB-201993
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
SB-201993 is a selective leukotriene B₄ (LTB4) receptor antagonist with a Ki=7.6 nM for LTB4 receptors on human inflammatory cells. SB-201993 inhibits calcium mobilization in inflammatory cells and 5-lipoxygenase activity, exerting anti-inflammatory effects. SB-201993 is promising for research of inflammatory diseases (e.g., dermatitis, arthritis) [1].
150399-22-7
12352005
Leukotriene Receptor
GPCR/G Protein
Inflammation/Immunology
O=C(O)C1=CC=CC(CSCC2=NC(/C=C/C(O)=O)=C(OCCCCCCCCC3=CC=C(OC)C=C3)C=C2)=C1
C32H37NO6S
563.70
[1]Sarau HM, et al. In vitro and in vivo pharmacological characterization of SB 201993, an eicosanoid-like LTB4 receptor antagonist with anti-inflammatory activity. Prostaglandins Leukot Essent Fatty Acids. 1999 Jul;61 (1) :55-64.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-19198/
Reference compound1
Phase 2
LTB4
Beschrijving
SB-201993 is a selective leukotriene B₄ (LTB4) receptor antagonist with a Ki=7.6 nM for LTB4 receptors on human inflammatory cells. SB-201993 inhibits calcium m
Specificaties
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