SB-216641
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
SB-216641 is a selective 5-HT1b antagonist. SB-216641 mildly prevents stress-induced behavioral performance dysregulations[1][2].
170230-39-4
12352100
5-HT Receptor
GPCR/G Protein; Neuronal Signaling
Neurological Disease
O=C(C1=CC=C(C2=C(C)C=C(C3=NOC(C)=N3)C=C2)C=C1)NC4=CC=C(C(OCCN(C)C)=C4)OC
C28H30N4O4
486.56
[1]Taylor R M, et al. Systemic Administration of the 5-HT1b Antagonist SB-216641 Prior to Acute Stress Exposure in Rats Mildly Prevents Stress-induced Behavioral Performance Dysregulations[J]. The Journal of Pharmacology and Experimental Therapeutics, 2024, 389: 115.|[2]Price GW, et al. SB-216641 and BRL-15572--compounds to pharmacologically discriminate h5-HT1B and h5-HT1D receptors. Naunyn Schmiedebergs Arch Pharmacol. 1997 Sep;356 (3) :312-20.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W903631/
Reference compound1
No Development Reported
5-HT1 Receptor
Beschrijving
SB-216641 is a selective 5-HT1b antagonist. SB-216641 mildly prevents stress-induced behavioral performance dysregulations[1][2].
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