
SB-247853
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
SB-247853 is a highly specific 5-HT2c receptor antagonist. SB-247853 induces orthostatic intolerance during head-up tilting. SB-247853 can be used in the research of cardiovascular diseases[1].
200711-10-0
12352005
H315-H319-H332-H335
5-HT Receptor
GPCR/G Protein; Neuronal Signaling
Neuroscience-Neuromodulation
Cardiovascular Disease
O=C(N1CCC2=C1C=C(C(F)(F)F)C(C)=C2)NC3=CC=C(OCC4=NC=CC=C4)N=C3
C22H19F3N4O2
428.41
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501
[1]Theis J G, et al. Orthostatic intolerance induced by the 5‐HT2C antagonist SB‐247853 in healthy volunteers during head‐up tilting. Clinical Pharmacology & Therapeutics, 2005, 77 (2) : P66-P66.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-19297/
Reference compound1
Phase 1
5-HT2 Receptor
Beschrijving
SB-247853 is a highly specific 5-HT2c receptor antagonist. SB-247853 induces orthostatic intolerance during head-up tilting. SB-247853 can be used in the resear
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