SC-560
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
SC-560 is a highly selective (700-fold selective over COX-2) and potent (IC50 = 9 nM) inhibitor of cyclooxygenase-1 (COX-1) .1 SC-560 inhibited TNFa-induced PGE2 synthesis in neurons and, PGE2 and thromboxane A2 synthesis in human monocytes and platelets (IC50’s = 1.8 nM and 2.5 nM respectively) indicating non-selective COX inhibition. SC-560 was able to inhibit PGE2 synthesis in COX-1-deficient neurons indicating a COX-1 independent mechanism. This unselective COX inhibition was only observed in whole cells – it remained COX-1 specific in cell lysates.2
Unconjugated
Brown solid
-20°C
Beschrijving
SC-560 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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