SCD34 Recombinant eiwit

CD34 is a highly glycosylated type I membrane protein that is selectively expressed on hematopoietic stem cells and vascular endothelium. It has been widely used as a molecular marker for the identification, isolation, and manipulation of hemopoietic stem cells and progenitors. CD34 can function as a regulator of hemopoietic cell adhesion by mediating the attachment of stem cells to bone marrow stromal cells or other bone marrow components. The full length human CD34 is a 385 amino acid protein, consisting of a 31 amino acid signal sequence, a 74 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain and a 259 amino acid extracellular domain. Recombinant human sCD34 is a 258 amino acid polypeptide containing only the extracellular domain of the full length CD34 protein.

947

P28906

NP_001020280.1

Recombinant Proteins

CHO cells

Cancer, Cell Cycle, Homeostasis, Immunology, Innate Immunity, Neuroscience, Signal Transduction, Stem Cell

Greater than 95% by SDS-PAGE gel and HPLC analyses.

Room Temp

The lyophilized sCD34 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted sCD34 stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing sCD34 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

CD34 molecule

Homo sapiens

Hematopoietic progenitor cell antigen CD34

Human

68342038

Lyophilized