SCFR-Fc Chimera, menselijk, gezuiverd Recombinant eiwit

Stem Cell Factor Receptor (SCFR) is a member of the receptor tyrosine kinase family. Binding of SCFR to its ligand Stem Cell Factor (PE-2008-5) induces receptor dimerization, autophosphorylation and signal transduction. SCFR is essential for the development of normal hematopoietic cells and plays an important role in the survival, proliferation and differentiation of mast cells, melanocytes and germ cells.

Stem cell factor receptor (SCFR) -Fc Chimera, purified human recombinant protein, suitable to block.

Mast/stem cell growth factor receptor; SCFR; Proto-oncogene tyrosine-protein kinase Kit; c-kit; CD117

P10721

Stem cell factor receptor (SCFR)

A DNA sequence encoding the signal peptide and extracellular domain of human Stem Cell Factor Receptor (amino acids 1-520) was fused to the Fc region of human IgG1 (amino acids 93-330) . The chimeric protein was expressed in modified human 293 cells.

Block

Purified. The SCFR-Fc Chimera consists of 5-45% carbohydrate by weight.

When reconstituted in 0.5 mL sterile phosphate-buffered saline, the solution will contain 1% human serum albumin (HSA) and 10% trehalose.

For research use only.

25°C (ambient)

It is recommended that 0.5 mL of sterile phosphate-buffered saline be added to the vial. Lyophilized products should be stored at 2 to 8°C. Following reconstitution short-term storage at 2-8°C is recommended, and longer-term storage of aliquots at -18 to -20°C. Repeated freeze thawing is not recommended.

>95% purity, as determined by SDS-PAGE and visualized by silver stain

HEK293

Lyophilized