SCN1B Antilichaam

Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. This gene encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.

6324

Q07699

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 19-160 of human SCN1B (NP_950238.1) .

Unconjugated

Primary Antibodies

Cancer, Neuroscience, Signal Transduction

Affinity purification

SH-SY5Y

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 30kDa

IgG

SCN1B

A-549

HeLa

MCF7

Mouse brain

Rat brain

Sodium channel, voltage-gated, type I, beta subunit

Homo sapiens

SCN1B, GEFSP1, ATFB13, BRGDA5

WB, IHC

Liquid