SCP2 Antilichaam - middelste regio : HRP (ARP56538_P050-HRP)

Sterol carrier protein 2

NLTP, SCOX, SCPX, SCP-2, SCP-X, NSL-TP, SCP-CHI

6342

Q6NXF4

NP_001007099

Human, Mouse, Rat, Guinea Pig, Horse, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human SCP2

SCP2 protein is thought to be an intracellular lipid transfer protein. SCP2 is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis.This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. The full-length nature of all transcript variants has not been determined.

TRIP13; UBC; PEX5; MPLKIP; MRRF; SUGP1; MRPS28; TBL2; SRRM2; RAB31; SEPT9; TIMM44; ECI2; SCO2; AGPS; STX7; UBL4A; VDAC3; VDAC2; RRBP1; RBMS1; NDUFA7; IDH3G; HSD17B4; ACAA1; RAB8A; ELAVL1; CACNA1A; ACAA2; EHHADH; CAV1; ACOX1; PITPNA

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rat: 100%; Zebrafish: 93%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

35kDa

Stanley, W.A., (2007) Arch. Biochem. Biophys. 461 (1), 50-58

Wet Ice

322

SCP2

SCP2

Rabbit

Non-specific lipid-transfer protein

NM_001007098

NHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQCCPTSDGAAAAILA