SCT200
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
SCT200 is a fully humanized IgG1 anti-EGFR monoclonal antibody with a Kd of 0.08 nM. SCT200 can kill tumor cells by complement-dependent cytotoxicity (CDC) and antibody-dependent cellular cytotoxicity (ADCC) through the Fc. SCT200 can be used for the study of refractory RAS and BRAF wild-type metastatic colorectal cancer[1].
12352203
EGFR
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Cancer-Kinase/protease
Cancer
[1]Yang L, et al. Efficacy, safety and genomic analysis of SCT200, an anti-EGFR monoclonal antibody, in patients with fluorouracil, irinotecan and oxaliplatin refractory RAS and BRAF wild-type metastatic colorectal cancer: a phase II study. EBioMedicine. 2024 Feb;100:104966.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P991507/
Inhibitory Antibodies
No Development Reported
Beschrijving
SCT200 is a fully humanized IgG1 anti-EGFR monoclonal antibody with a Kd of 0.08 nM. SCT200 can kill tumor cells by complement-dependent cytotoxicity (CDC) and
Specificaties
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