SCYE1 Antilichaam - middengebied: Biotine (ARP40552_P050-Biotine)

Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

P43, HLD3, EMAP2, SCYE1, EMAPII

9255

Q12904

NP_004748

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Yeast, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human SCYE1

SCYE1 is a cytokine that is specifically induced by apoptosis. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor of SCYE1 (pro-SCYE1) is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex. Therefore, pro-SCYE1 may function in binding RNA as part of the tRNA synthetase complex in normal cells and in stimulating inflammatory responses after proteolytic cleavage in tumor cells. The protein encoded by this gene is a cytokine that is specifically induced by apoptosis. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor of SCYE1 (pro-SCYE1) is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex. Therefore, pro-SCYE1 may function in binding RNA as part of the tRNA synthetase complex in normal cells and in stimulating inflammatory responses after proteolytic cleavage in tumor cells. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

AIMP2; TSNAX; UBC; CCAR2; RPL36; EEF1E1; IQGAP1; VARS; RPLP0; RPL27A; RPL23A; RPL21; RPL17; RPL15; RPL13; RPL7A; RARS; QARS; PTBP1; PSMC6; MARS; KARS; IARS; DNAJA1; EIF4G1; EIF2S3; EIF2S1; DARS; PAN2; gag; HSP90B1; MAPK8; LARS; EPRS; APP; COPS5; CUL1; PSM

Biotin

Polyclonal Antibody

WB

Affinity Purified

AIMP1 is strongly supported by BioGPS gene expression data to be expressed in HEK293T

0.5 mg/ml

Cow: 93%; Dog: 86%; Horse: 93%; Human: 100%; Mouse: 92%; Pig: 93%; Rabbit: 100%; Rat: 93%; Yeast: 86%; Zebrafish: 92%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

34kDa

Bottoni, A., (2007) J. Cell. Physiol. 212 (2), 293-297

Wet Ice

312

AIMP1

AIMP1

Rabbit

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1

NM_004757

GTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDL