SDCBP Antilichaam - middengebied: Biotine (ARP44535 T100-Biotine)

Syndecan binding protein (syntenin)

ST1, MDA9, SYCL, MDA-9, TACIP18

6386

O00560

NP_001007068

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human SDCBP

SDCBP was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus.The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms.

WASL; SSNA1; CADPS; CGGBP1; ZBTB14; UBE2A; UBC; TRAF5; TFCP2; TDO2; FAM118B; DCTPP1; PYCRL; NADK; CDCP1; RIC8A; KLHL12; HOMEZ; TRIM54; EIF5A2; SEPT3; PRPF40A; NAGK; C11orf57; CEP55; ENOX1; FAM118A; THG1L; C1orf109; ZCCHC10; KCTD9; ROPN1; LZTFL1; NECAB2; P

Biotin

Polyclonal Antibody

IHC, WB

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

32kDa

Boukerche, H., (2005) Cancer Res. 65 (23), 10901-10911

Wet Ice

298

SDCBP

SDCBP

Rabbit

Syntenin-1

NM_001007067

VGIRRAEIKQGIREVILCKDQDGKIGLRLKSIDNGIFVQLVQANSPASLV