SDF-1 bèta (CXCL12)

SDF-1α and β are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor. Recombinant murine SDF-1β is a 8.5 kDa protein containing 72 amino acid residues.

Pxorf31

912189

P40224

NP_068350.1

NM_021704

6 F1; 6 53.0 cM

Mouse

Human, Mouse

KPVSLSYRCP CRFFESHIAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNKRL KM

< 0.1 ng/µg of protein (< 1EU/µg)

> 98% by SDS-PAGE & HPLC analyses

Determined by its ability to chemoattract human monocytes using a concentration range of 50.0-100.0 ng/ml.

72

Lyophilized

8.5 kDa

E. coli