SDF-1 bèta (CXCL12)

SDF-1α and β are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor. Recombinant rat SDF-1β is an 8.4 kDa protein containing 72 amino acid residues.

Cxcl12; Sdf1

24772

Q9QZD1

NP_071513.1

NM_022177.3

4q42.1

Rat

Human

KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNKRL KM

< 0.1 ng/µg of protein (< 1EU/µg)

> 95% by SDS-PAGE & HPLC analyses

Determined by its ability to chemoattract human monocytes using a concentration range of 100.0-200.0 ng/ml.

72

Lyophilized

8.4 kDa

E. coli