SDHAF1 Antilichaam

SDHAF1 Antibody: SDHAF1 (Succinate dehydrogenase complex assembly factor 1) is one of the subunits of the succinate dehydrogenase (SDH) complex (or complex II) of the mitochondrial respiratory chain. SDHAF1 resides in the mitochondria, and is essential for SDH assembly, but does not physically associate with the complex in vivo. Mutations in this gene are associated with SDH-defective infantile leukoencephalopathy (mitochondrial complex II deficiency) . Unlike the related protein SDHAF2, SDHAF1 is not thought to be a tumor suppressor.

644096

A6NFY7

NP_001036096

Human, Mouse

Unconjugated

Primary Antibodies

Homeostasis

SDHAF1 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1282 - 3T3 (NIH) Cell Lysate

1 mg/mL

SDHAF1 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

SDHAF1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

SDHAF1 antibody is predicted to not cross-react with other SDHAF protein family members.

SDHAF1

Cat. No. 17-201 - 3T3/BALB Cell Slide

Succinate dehydrogenase complex assembly factor 1

Homo sapiens

Ghezzi D, Goffrini P, Uziel G, et al. SDHAF1, encoding a LYR complex-II specific assembly factor, is mutated in SDH-defective infantile leukoencephalopathy. Nat. Genet. 2009; 41:654-6.

Hensen EE and Bayley JP. Recent advances in the genetics of SDH-related paraganglioma and pheochromocytoma. Fam. Cancer 2011; 10:355-63.

SDHAF1 Antibody: LYRM8, LYRM8, Succinate dehydrogenase assembly factor 1, mitochondrial, LYR motif-containing protein 8, SDH assembly factor 1

ELISA, WB, ICC, IF

111038124

Liquid