SEK1 / MKK4 (fosfo Ser80) Antilichaam

Dual specificity kinase that activates the JUN kinases MAPK8 (JNK1) and MAPK9 (JNK2) as well as MAPK14 (p38) but not MAPK1 (ERK2) or MAPK3 (ERK1) .

6416

P45985

NP_003001.1

Human, Mouse, Rat

SEK1/MKK4 (Phospho-Ser80) antibody was raised against a peptide sequence around phosphorylation site of serine 80 (T-H-S (p) -I-E) derived from Human SEK1/MKK4.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

44 kDa

This antibody detects endogenous level of SEK1/MKK4 only when phosphorylated at serine 80.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

MAP2K4

Mitogen-activated protein kinase kinase 4

Homo sapiens

Park HS, et al. (2002) J Biol Chem; 277 (4) : 2573-8.

JNKK, MEK4, MKK4, SEK1, SKK1, JNKK1, SERK1, MAPKK4, PRKMK4, SAPKK1, SAPKK-1, SRK, JNKK, MAP2K4, MAPK/ERK kinase 4, MAPKK 4

WB, IHC, IF

4506889

Liquid