Selenomethionine-77se

Selenomethionine-77Se (Seleno-DL-methionine-77Se) is the 77Se- labeled Selenomethionine. Selenomethionine is a naturally occurring amino acid containing selenium that has oral activity and is a common natural food source. Selenomethionine has antitumor activity[1][2][3].

1414810-73-3

12352211

Autophagy; Isotope-Labeled Compounds; Keap1-Nrf2

Autophagy; NF-κB; Others

Cancer

OC(C(N)CC[77Se]C)=O

C5H11NO2 77Se

194.07

[1]Kupsco A, et al. Mechanisms of selenomethionine developmental toxicity and the impacts of combined hypersaline conditions on Japanese medaka (Oryzias latipes) . Environ Sci Technol. 2014 Jun 17;48 (12) :7062-8. |[2]Redman C, et al. Inhibitory effect of selenomethionine on the growth of three selected human tumor cell lines. Cancer Lett. 1998 Mar 13;125 (1-2) :103-10. |[3]Wang P, et al. Selenium Attenuates TBHP-Induced Apoptosis of Nucleus Pulposus Cells by Suppressing Mitochondrial Fission through Activating Nuclear Factor Erythroid 2-Related Factor 2. Oxid Med Cell Longev. 2022 Apr 11;2022:7531788.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-B1000S1/

Isotope-Labeled Compounds

No Development Reported