β-Selineen

β-Selinene is a sesquiterpene and is the main active component of the essential oil of red purple hibiscus (Callicarpa macrophylla) . β-Selinene exhibits significant related antioxidant activity, anti-inflammatory activity, and antipyretic analgesic activity. β-Selinene may exert antioxidant effects by directly scavenging free radicals (DPPH, NO, •OH) and chelating pro-oxidative metal ions (Fe²⁺) ; inhibit cyclooxygenase (COX) activity, reduce prostaglandin (such as PGE₂) synthesis to exert anti-inflammatory effects; regulate the thermoregulatory set point of the hypothalamus and inhibit inflammatory mediators to exert antipyretic and analgesic effects[1].

17066-67-0

12352211

COX; Endogenous Metabolite

Immunology/Inflammation; Metabolic Enzyme/Protease

COVID-19-immunoregulation

Neurological Disease; Inflammation/Immunology

C[C@]12[C@]([H])(C(CCC2)=C)C[C@@H](CC1)C(C)=C

C15H24

204.35

[1]Chandra M, et al. β-Selinene-Rich Essential Oils from the Parts of Callicarpa macrophylla and Their Antioxidant and Pharmacological Activities. Medicines (Basel) . 2017 Jul 10;4 (3) :52.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W747297/

Reference compound1

No Development Reported