Selumetinib (AZD6244)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
606143-52-6
ARRY-142886
C07429-200mg
MEK
Protein Tyrosine Kinase
CN1C=NC2=C1C=C (C (=C2F) NC3=C (C=C (C=C3) Br) Cl) C (=O) NOCCO
C17H15BrClFN4O3
Selumetinib (AZD6244, ARRY-142886) is a potent, highly selective MEK inhibitor with IC50 of 14 nM for MEK1 and Kd value of 530 nM for MEK2. It also inhibits ERK1/2 phosphorylation with IC50 of 10 nM, no inhibition to p38α, MKK6, EGFR, ErbB2, ERK2, B-Raf, etc. Selumetinib suppresses cell proliferation, migration and trigger apoptosis. Phase 3.
2 years -80 in solvent
Beschrijving
Selumetinib (AZD6244) Beschikbaar in 50 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
Specificaties
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