SENP3 Antilichaam - N-terminaal gebied: Biotine (ARP55322 P050-Biotine)

SUMO1/sentrin/SMT3 specific peptidase 3

SSP3, Ulp1, SMT3IP1

26168

Q9H4L4

NP_056485

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human SENP3

SENP3 is a protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. SENP3 deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability.

HIF1A; EP300; UBC; SUMO2; WDR5; ASH2L; KMT2D; RBBP5; KMT2A; MEN1; RNF2; HECW2; SOX2; LAS1L; PELP1; CDK6; CDK4; MOV10; CHCHD4; DHX15; ILF3; TRIM63; TRIM54; USP21; USP15; CDKN2A; RPS18; RPS11; RPS8; RPS4X; RPLP0; NPM1; PIDD1; NR1H2; TP53; MDM2; STUB1; HSP90

Biotin

Polyclonal Antibody

IF, WB

Affinity Purified

SENP3 is strongly supported by BioGPS gene expression data to be expressed in 721_B. HeLa

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

65kDa

Haindl, M., (2008) EMBO Rep. 9 (3), 273-279

Wet Ice

574

SENP3

SENP3

Rabbit

Sentrin-specific protease 3

NM_015670

PPPKPRLKSGGGFGPDPGSGTTVPARRLPVPRPSFDASASEEEEEEEEEE