Sepantroniumbromide (YM155)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
781661-94-7
C16133-10mg
Survivin
Apoptosis
CC1=[N+] (C2=C (N1CCOC) C (=O) C3=CC=CC=C3C2=O) CC4=NC=CN=C4.[Br-]
C20H19BrN4O3
Sepantronium Bromide (YM155) is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0.54 nM in HeLa-SURP-luc and CHO-SV40-luc cells; does not significantly inhibit SV40 promoter activity, but is observed to slightly inhibit the interaction of Survivin with XIAP. YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells. Phase 2.
2 years -80 in solvent
Beschrijving
Sepantroniumbromide (YM155) Beschikbaar in 10 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
Specificaties
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