SERPINI1 Antilichaam

This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.

5274

Q99574

Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 181-410 of human SERPINI1 (NP_005016.1) .

Unconjugated

Primary Antibodies

Neuroscience

Affinity purification

Mouse brain

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 46kDa

IgG

SERPINI1

Rat brain

Serpin peptidase inhibitor, clade I (neuroserpin), member 1

Homo sapiens

PI12, neuroserpin, PI12, Neuroserpin, Peptidase inhibitor 12, PI-12

WB, IHC, IF

Liquid