SESTD1 Antilichaam

SESTD1 Antibody: SESTD1 was initially identified in mutant zebrafish with defects in the spontaneous contraction and touch response as a novel gene, solo, encoding a protein containing SEC14 and spectrin repeat domains. Other experiments indicated that SESTD1 interacts with the TRPC4 and TRPC5, members of the transient receptor potential channel family, via the TRPC calmodulin- and inositol 1, 4, 5-triphosphate receptor-binding domain and is essential for efficient receptor-mediated activation of TRPC5, suggesting that SESTD1 is a novel regulator of these TRPC proteins.

91404

Q86VW0

NP_835224

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Signal Transduction

SESTD1 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1463 - Rat Brain Tissue Lysate

1 mg/mL

SESTD1 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

SESTD1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

SESTD1

Cat. No. 10-301 - Human Brain Tissue Slide

SEC14 and spectrin domains 1

Homo sapiens

Sato T and Mishina M. Representational difference analysis, high-resolution physical mapping, and transcript identification of the zebrafish genomic region for a motor behavior. Genomics2003; 82:218-29.

Miehe S, Bieberstein A, Arnold I, et al. The phospholipid-binding protein SESTD1 is a novel regulator of the transient receptor potential channels TRPC4 and TRPC5. J. Biol. Chem.2010; 285:12426-34.

SESTD1 Antibody: SOLO, SOLO, SEC14 domain and spectrin repeat-containing protein 1, Huntingtin-interacting protein-like protein

ELISA, WB, IHC-P, IF

188528641

Liquid