SETD2 Antilichaam

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.

29072

Q9BYW2

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 803-1103 of human SETD2 (NP_054878.5) .

Unconjugated

Primary Antibodies

Other

Affinity purification

HeLa

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 288kDa

IgG

WB: 1:500 - 1:2000

SETD2

Jurkat

SET domain containing 2

Homo sapiens

SETD2, FLJ16420, FLJ22472, FLJ23184, FLJ45883, HIF-1, HSPC069, HYPB, KIAA1732, KMT3A, SET2, HIP-1, HBP231, p231HBP

WB

Liquid