SETMAR Antibody - C-terminal regio : HRP (ARP51245 P050-HRP)

SET domain and mariner transposase fusion gene

Mar1, METNASE

6419

E7EN68

NP_001230652

Human, Cow

The immunogen is a synthetic peptide directed towards the C-terminal region of Human SETMAR

This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain.

CHEK1; H3F3C; tat; PRPF19; SETMAR; RAD9A; PCNA; TOP2A; XRCC4

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Human: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

59kDa

Wet Ice

545

SETMAR

SETMAR

Rabbit

Histone-lysine N-methyltransferase Ensembl ENSP00000403145

FLQGKRFHNQQDAENAFQEFVESQSTDFYATGINQLISRWQKCVDCNGSY