SF1 (fosfo Ser82) Antilichaam

Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor.

7536

Q15637

NP_004621.2

Human, Mouse

SF1 (phospho Ser82) antibody was raised against a peptide sequence around phosphorylation site of Serine 82 (S-P-S (p) -P-E) derived from Human SF1.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

68 kDa

IgG

The antibody detects endogenous levels of SF1 only when phosphorylated at serine 82.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

SF1

Splicing factor 1

Homo sapiens

Susan Y. Park, Development, May 2005; 132: 2415 - 2423.

Dujin Zhou, Mol. Endocrinol., Jul 2000; 14: 986.

Dagmar Wilhelm, Genes & Dev., Jul 2002; 16: 1839.

Philipp Gut, Development, Oct 2005; 132: 4611 - 4619.

BBP, CW17, SF01, ZFM1, ZNF162

WB, IHC

42544130

Liquid