SF3A3 Antilichaam - middengebied: Biotine (ARP40684_P050-Biotine)

Splicing factor 3a, subunit 3, 60kDa

PRP9, PRPF9, SAP61, SF3a60

10946

Q12874

NP_006793

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human SF3A3

SF3A3 is the subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP.This This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

TRIM69; HUWE1; ZNF212; TADA2A; FUS; UBC; NEDD8; MDM2; WWOX; RNF2; SUZ12; EED; rev; APBB1; ACTN1; ACTN4; STAM2; HGS; SNRPB; CDAN1; PRPF40A; WBP4; TCERG1; UBD; SF3A1; FN1; gag-pol; PRMT5; PRPF19; PRPF31; SF3B1; SF3B3; SF3B4; HNRNPR; DDX46; TOX4; DDX23; PRPF

Biotin

Polyclonal Antibody

WB

Affinity Purified

SF3A3 is supported by BioGPS gene expression data to be expressed in 721_B

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 91%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

59kDa

Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007)

Wet Ice

501

SF3A3

SF3A3

Rabbit

Splicing factor 3A subunit 3

NM_006802

THENVQRKQARTGEEREEEEEEQISESESEDEENEIIYNPKNLPLGWDGK

3