SFN Antilichaam - middengebied: FITC (ARP54792_P050-FITC)

Stratifin

YWHAS

2810

P31947

NP_006133

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Yeast, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human SFN

SFN is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. SFN binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, SFN regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.

FAM9B; RAB3IP; LONRF1; CCDC102B; ZC2HC1C; DTL; FAM53C; MKRN3; FOXO4; MAGEA1; CCNH; SIK3; ZFYVE19; YWHAZ; VCL; UBE2V1; SNRPF; UBE2R2; PAK2; G6PD; TARDBP; EGFR; BAD; MARK3; HDAC7; HDAC5; HDAC4; RAF1; CDC25C; MST1R; ABL1; HNRNPD; ATF2; TRIM32; COPS6; UBC; TP

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB, IHC

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Yeast: 93%; Zebrafish: 86%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

28kDa

Yang, W., (2008) Cell Cycle 7 (5), 670-682

Wet Ice

248

SFN

SFN

Rabbit

14-3-3 protein sigma

NM_006142

FHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLT