SFRP1 Polyklonale Antilichaam

Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity) . Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity) . In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity) . Inhibits WNT1/WNT4-mediated TCF-dependent transcription.

FRP; FRP1; FrzA; FRP-1; SARP2; Secreted frizzled-related protein 1; sFRP-1; Secreted apoptosis-related protein 2; SARP-2; SFRP1

6422

Q8N474

Secreted

Human, Mouse, Rat

201-314/314

SFRP1

Unconjugated

KLH conjugated synthetic peptide derived from human SFRP1

WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

1µg/µl

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

6422