SGMS2 Antilichaam

Sphingomyelin, a major component of cell and Golgi membranes, is made by the transfer of phosphocholine from phosphatidylcholine onto ceramide, with diacylglycerol as a side product. SGMS2 is an enzyme that catalyzes this reaction primarily at the cell membrane. The synthesis is reversible, and this enzyme can catalyze the reaction in either direction. This protein is required for cell growth.

166929

Q8NHU3

Q8NHU3

Human, Mouse

This SGMS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 338-365 amino acids from the C-terminal region of human SGMS2.

Unconjugated

Primary Antibodies

Cancer, Obesity, Signal Transduction

This antibody is purified through a protein A column, followed by peptide affinity purification.

Batch dependent

Predicted species reactivity based on immunogen sequence: Monkey, Rat

Supplied in PBS with 0.09% (W/V) sodium azide.

None

Blue Ice

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

42 kDa

Rabbit Ig

For WB starting dilution is: 1:1000

SGMS2

Phosphatidylcholine:ceramide cholinephosphotransferase 2

Homo sapiens

Ternes, P., et al. J. Lipid Res. 50 (11) :2270-2277 (2009)

Liu, J., et al. Arterioscler. Thromb. Vasc. Biol. 29 (6) :850-856 (2009)

Tani, M., et al. Biochem. Biophys. Res. Commun. 381 (3) :328-332 (2009)

Phosphatidylcholine:ceramide cholinephosphotransferase 2, Sphingomyelin synthase 2, SGMS2, SMS2

WB

44888519

Liquid