SGSM2 Antilichaam

SGSM2 Antibody: Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM2 is a Rab9A effector that activates GTP hydrolysis by Rab32 and Rab33B proteins.

9905

O43147

NP_055668

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Neuroscience

SGSM2 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1362 - Human Cerebellum Tissue Lysate

1 mg/mL

SGSM2 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

SGSM2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

116 kDa

IgG

Multiple isoforms of SGSM2 are known to exist. SGSM2 antibody is predicted to not cross react with other SGSM family proteins.

SGSM2

Cat. No. 10-301 - Human Brain Tissue Slide

Small G protein signaling modulator 2

Homo sapiens

Bar-Sagi D and Hall A. Ras and Rho GTPases: a family reunion. Cell 2000; 103:227-38.

Colicelli J. Human ras superfamily proteins and related GTPases. Sci. STKE 2004; 250:RE13

Yang H, Sasaki T, Minoshima S, et al. Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB) -mediated signaling pathway. Genomics 2007; 90:249-60.

Nottingham RM, Ganley IG, Barr FA, et al. RUTBC1 protein, a Rab9A effector that activates GTP hydrolysis by Rab32 and Rab33B proteins. J. Biol. Chem. 2011; 286:33213-22.

SGSM2 Antibody: RUTBC1, KIAA0397, RUTBC1, Small G protein signaling modulator 2, RUN and TBC1 domain-containing protein 1

ELISA, WB, IF

148612795

Liquid