SH3BP2 Antilichaam

The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.

6452

P78314

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 392-561 of human SH3BP2 (NP_001116153.1) .

Unconjugated

Primary Antibodies

Signal Transduction

Affinity purification

A-549

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 75kDa/80kDa

IgG

WB: 1:500 - 1:2000

SH3BP2

Mouse spleen

Mouse lung

SH3-domain binding protein 2

Homo sapiens

SH3BP2, 3BP2, CRBM, CRPM, FLJ42079, RES4-23, 3BP-2

WB

Liquid