SH3BP4 Antilichaam

SH3BP4 Antibody: SH3BP4 was initially isolated as a novel cDNA using differential display analysis using cultured human corneal fibroblasts. The protein contains three Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. SH3BP4 has been shown to interact with specific endocytic proteins such as clathrin, dynamin, and the transferrin receptor (TfR) and localizes to TfR-containing coated pits and vesicles. It is thought to be involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of TfR. At least two isoforms of SH3BP4 are known to exist.

23677

Q9P0V3

NP_055336

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Homeostasis

SH3BP4 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1462 - Rat Lung Tissue Lysate

1 mg/mL

SH3BP4 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

SH3BP4 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

SH3BP4

Cat. No. 10-101 - Human Lung Tissue Slide

SH3-domain binding protein 4

Homo sapiens

Dunlevy JR, Berryhill BL, Vergnes JP, et al. Cloning, chromosomal localization, and characterization of cDNA from a novel gene, SH3BP4, expressed by human corneal fibroblasts. Genomics1999; 62:519-24.

Tosoni D, Puri C, Confalonieri S, et al. TTP specifically regulates the internalization of the transferrin receptor. Cell2005; 123:875-888.

SH3BP4 Antibody: TTP, BOG25, EHB10, TTP, SH3 domain-binding protein 4, EH-binding protein 10

ELISA, WB, IHC-P

7657562

Liquid