SH3GL1 Antilichaam

SH3GL1 may play a regulatory role in synaptic vesicle recycling. It interacts with SYNJ1 and DNM1 through its SH3 domain with the proline-rich region of mixed lineage Leukemia (MLL) in either the fusion or the normal MLL protein. This protein is located in cytoplasmic, and peripheral membrane protein associated with internal membranes. Concentrated in presynaptic nerve terminals in neurons (By similarity) . It’s expressed ubiquitously. Higher expression in pancreas, placenta, prostate, testis and uterus. In some cases of acute leukemia, a translocation results in the formation of a MLL-EEN fusion gene.

6455

Q99961

NP_003016.1

Human, Mouse, Rat

1-360

Unconjugated

Primary Antibodies

Neuroscience, Signal Transduction

Immunoaffinity Purified

1 mg/mL

Phosphate-Buffered Saline. No preservatives added.

None

Blue Ice

SH3GL1 antibody can be stored at 4˚ C for short term (weeks) . Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

39.8 kDa (calculated)

SH3-containing Grb-2-like 1 protein antibody can be used for the detection of SH3-containing Grb-2-like 1 protein by Western Blot.

SH3GL1

SH3-domain GRB2-like 1

Homo sapiens

CNSA1, SH3D2B, Endophilin-A2, EEN fusion partner of MLL, EEN, CNSA1, SH3P8, SH3containing Grb2like 1 protein

WB

4506929

Liquid