SHISA9 Antilichaam

SHISA9 Antibody: Shisa proteins are a recently-identified family of modulators of both FGF and Wnt signaling that block both maturation and transport to the cell surface of their respective receptors. SHISA9, also known as CKAMP44a, is a brain-specific type I transmembrane protein that associates with AMPA receptors in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses. It is thought to modulate short-term plasticity at specific excitatory synapses.

729993

B4DS77

NP_001138676

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Signal Transduction

SHISA9 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1463 - Rat Brain Tissue Lysate

1 mg/mL

SHISA9 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

SHISA9 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

SHISA9

Cat. No. 10-301 - Human Brain Tissue Slide

Shisa homolog 9 (Xenopus laevis)

Homo sapiens

Hedge TA and Mason I. Expression of Shisa2, a modulator of both Wnt and Fgf signaling, in the chick embryo. Int. J. Dev. Biol.2008; 52:81-5.

Von Engelhardt J, Mack V, Sprengel R, et al. CKAMP44: a brain-specific protein attenuating short-term synaptic plasticity in the dentate gyrus. Science2010; 327:1518-22.

O'Donovan MC, Craddock N, Norton N, et al. Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nat. Genet.2008; 40:1053-5.

SHISA9 Antibody: CKAMP44, Protein shisa-9

ELISA, WB, IHC-P, IF

291463300

Liquid