SHMT1 Antilichaam

This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants.

6470

P34896

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 285-444 of human SHMT1 (NP_683718.1) .

Unconjugated

Primary Antibodies

Signal Transduction

Affinity purification

293T

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 53kDa

IgG

WB: 1:500 - 1:2000

SHMT1

HepG2

HT-29

K-562

A375

Mouse liver

Serine hydroxymethyltransferase 1 (soluble)

Homo sapiens

SHMT1, 14 kDa protein, CSHMT, Serine methylase, SHMT

WB

Liquid