SHMT2 Antilichaam

This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants.

6472

P34897

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 265-504 of human SHMT2 (NP_005403.2) .

Unconjugated

Primary Antibodies

Cancer, Signal Transduction

Affinity purification

HeLa

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 52kDa

IgG

SHMT2

OVCAR3

22Rv1

Mouse liver

Mouse kidney

Serine hydroxymethyltransferase 2 (mitochondrial)

Homo sapiens

SHMT2, GLYA, SHMT, HEL-S-51e

WB, IHC, IF

Liquid